HLA Alloantibodies in Multiparous Women at Abidjan
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چکیده
منابع مشابه
HLA Alloantibodies in Multiparous Women at Abidjan
Serum of multiparous women can contain HLA polyclonal antibodies which can be used as reagents for serological typing of HLA class I and class II. The aim of this study was to investigate an alloimmunization of multiparous women and to identify HLA polyclonal antibodies which could be useful as laboratory reagents in view of the future HLA unit of the Department of Immunology at Abidjan. In an ...
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The role of alloantibodies against HLA and non-HLA targets is becoming increasingly recognized as critical in the pathogenesis of acute and chronic renal allograft outcomes. This review discusses the antigenic targets, the mechanisms of T and B cell activation that result in the production of antibody, the complement cascade, methods of antibody detection, and the evidence that alloantibody-med...
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The impact of donor-specific HLA alloantibodies (DSA) on short- and long-term liver transplant outcome is not clearly defined. While it is clear that not all levels of allosensitization produce overt clinical injury, and that liver allografts possess some degree of alloantibody resistance, alloantibody-mediated adverse consequences are increasingly being recognized. To better define the current...
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Aims: The frequencies of alloantibodies to platelet glycoproteins and HLA class 1 have not been reported in this part of the world. To determine the prevalence of these antibodies in Nigeria. Methods: The sera of 100 multiparous women were tested for antibodies to HPA and HLA class 1 antigens using GTI PakPlus solid phase ELISA Kit in a cross sectional study. Results: The prevalence of platelet...
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ژورنال
عنوان ژورنال: International Journal of Immunology
سال: 2016
ISSN: 2329-177X
DOI: 10.11648/j.iji.20160406.13